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Scientists Create Novel Genetic Model of Down Syndrome in Rats

Scientists Create Novel Genetic Model of Down Syndrome in Rats
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United statesHaruka takayamaSachiko miyagawa tomitaMasaharu hiratsukaYoshio hataYicong liRogerh reevesSatoko matsukuraMasumi hirabayashiFeng gaoYasuhiro kazukiHanna moyerHiromasa haraRoger reevesJohns hopkinsKanako kazuki

Pain neuron-derived peptide prevents endotoxic death by targeting kynurenine pathway in microglia

Pain neuron-derived peptide prevents endotoxic death by targeting kynurenine pathway in microglia
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Kenta maruyamaProfessor takeshi kondo at hokkaido universityNational institute for physiological sciencesHokkaido universityNational institutePhysiological sciencesAssistant professor takeshi kondo

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A research team led by the National Institute for Physiological Sciences and joined by Hokkaido University explored the role of pain neurons in the re..

Erika sugisawaKenta maruyamaLife sciencesProfessor takeshi kondo at hokkaido universityNational institute for physiological sciencesHokkaido universityAlphagalileo readerStandard levelPremium levelNational institutePhysiological sciencesAssistant professor takeshi kondo

Study finds how brain perceives indistinct familiar objects

Researchers from the National Institute for Physiological Sciences in Japan have found how our brain can perceive familiar objects even when they become indistinct.

Yumiko yoshimuraNational institute for physiological sciencesNational institutePhysiological sciencesRie kimuraScience advancesEws india

Study reveals link between changes of neuronal activities and dyskinesia

Study reveals link between changes of neuronal activities and dyskinesia Many people with Parkinson s disease develop abnormal movements called L-DOPA induced dyskinesia, a major side effect of long-term medication. The mechanism underlying this side effect has been unknown. In this study, researchers have revealed relation between changes of neuronal activities and dyskinesia. Parkinson s disease (PD) is the common age-related neurological disorder affecting 7 - 10 million people worldwide. It is caused by loss of dopaminergic neurons in the brain region called the substantia nigra, and induces difficulty in execution of movements (akinesia), muscle stiffness (rigidity), walking difficulty, tremorous hand movements (tremor), and non-motor symptoms such as depression and sleep disturbance.

Atsushi nambuEmily hendersonNational institute for physiological sciencesNational institutePhysiological sciencesStudy corresponding authorஎமிலி ஹென்டர்சன்தேசிய நிறுவனம் க்கு உடலியல் அறிவியல்தேசிய நிறுவனம்உடலியல் அறிவியல்