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Dr Temitope Oke, a gastroenterologist at University College Hospital (UCH), Ibadan, in this interview by SADE OGUNTOLA, reveals that some cases of stomach
Background In Japan, the public insurance policy was revised in 2020 to cover hereditary breast and ovarian cancer (HBOC), including genetic testing and surveillance, for patients with breast cancer (BC). Consequently, the demand for risk-reducing salpingo-oophorectomy (RRSO) has increased. This study aimed to clarify the changes in the demand and timing of genetic testing and RRSO associated with public insurance coverage for HBOC in Japan.
Methods This retrospective analysis included 350 women with germline BRCA (g BRCA ) pathogenic variants (PVs) who had visited gynaecologists; they received g BRCA genetic testing at 45.1±10.6 (20–74) years. The use of medical testing and preventive treatment was compared between the preinsurance and postinsurance groups using Mann-Whitney U and Fisher’s exact tests.
Results The findings indicate that RRSO rates doubled from 31.4% to 62.6% among patients with g BRCA -PV. The implementation rate was 32.4% among unaffected carriers and 70.3%
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