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A genetic sequencing effort found more carriers of risk genes for hereditary breast and ovarian cancer or Lynch syndrome than would have been found by following existing genetic testing guidelines.
Whole-exome sequencing identified carriers of predisposition genes for hereditary breast and ovarian cancer or Lynch syndrome who, under current guidelines, would not have qualified for genetic testing, according to study results.The findings, presented at American Association for Cancer Research Annual Meeting, highlighted the need for wide genomic screening for inherited autosomal dominant