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Potential Genetic Marker Boosts Survival in Head, Neck Cancer

Potential Genetic Marker Boosts Survival in Head, Neck Cancer
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United statesNeda moatamedMustafa alaniIbraheem aliSaroj basakAlbert koWeihong yanKarolina elIsabelle liuJenna chatoffKimberly hwangMarco morselliDaniel shinNatarajan venkatesanBhavani shankara gowdaMarilene wang

Researchers uncover a potential genetic marke

Researchers uncover a potential genetic marke
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

United statesSaroj basakNatarajan venkatesanBhavani shankara gowdaMatteo pellegriniJungmo gahngJenna chatoffDaniel shinKimberly hwangNeda moatamedMarilene wangIsabelle liuIbraheem aliAlbert koMustafa alaniWeihong yan

Researchers uncover a potential genetic marker associated with better survival outcomes in patients with head and neck cancer

Researchers from the UCLA Health Jonsson Comprehensive Cancer Center show for the first time that a gene usually linked to giant axonal neuropathy, a rare and s

United statesAlbert koIsabelle liuIbraheem aliMustafa alaniWeihong yanMarco morselliKarolina elBhavani shankara gowdaNatarajan venkatesanSaroj basakMatteo pellegriniJungmo gahngJenna chatoffDaniel shinNeda moatamed

UCLA researchers uncover dual role of GAN gene in neurological disorder, head and neck cancer

Researchers from the UCLA Health Jonsson Comprehensive Cancer Center show for the first time that a gene usually linked to giant axonal neuropathy, a rare and severe neurological condition, also plays a role in inhibiting aggressive tumor cell growth in head and neck cancers.

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Gene could help predict response to cervical cancer treatment

FINDINGS UCLA researchers have identified a potential diagnostic marker that could help predict how likely someone with cervical cancer is to respond to the standard treatment of chemotherapy and radiation. The scientists found that PACS-1, a gene that resides on a small segment of the long arm of chromosome 11, is overexpressed in cancer tissues, which can result in cancer growth and spread. Further, they discovered that translocation of the PACS-1 protein from outside to inside the cell nucleus a function required for normal cell growth plays a role in the development of cervical cancer that is resistant to chemotherapy and radiation. Higher levels of PACS-1 expression in the nucleus could indicate resistance to the treatment, the researchers say.

Los angelesUnited statesGeffen school of medicineMolecular biology instituteNational cancer instituteDavid geffen school of medicineVeterans affairs greater los angeles healthcare systemJonsson comprehensive cancer centerEri srivatsanDavid geffen schoolComprehensive cancer centerMolecular biologyMysore veenaGeffen schoolVeterans affairs greater los angeles healthcareலாஸ் ஏஞ்சல்ஸ்