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Type 2 diabetes alters the behavior of discs in the vertebral column

Type 2 diabetes alters the behavior of discs in the vertebral column
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University of california san diegoUnited statesClaire acevedoDepartment of orthopaedic surgeryUniversity of utahScore centerResearch allocation committeeNational institutes of healthAerospace engineeringCalifornia san diegoAaron fieldsOrthopaedic surgeryMusculoskeletal biologyCalifornia officeNational institutesAdvanced light source

Study provides insight into potential mechanisms underlying diabetes-related disc tissue damage

Type 2 diabetes alters the behavior of discs in the vertebral column, making them stiffer, and also causes the discs to change shape earlier than normal.

San diegoUnited statesUniversity of california san diegoClaire acevedoNational institutes of healthResearch allocation committeeUniversity of utahScore centerDepartment of orthopaedic surgeryAerospace engineeringUniversity of californiaCalifornia san diegoAaron fieldsOrthopaedic surgeryMusculoskeletal biologyCalifornia office

Type 2 Diabetes Alters the Behavior of Discs in the Vertebral Column

Type 2 diabetes alters the behavior of discs in the vertebral column, making them stiffer, and also causes the discs to change shape earlier than normal.

University of california san franciscoUnited statesLawrence berkeley laboratoryUniversity of california san diegoSan franciscoRoberto ritchieJeffreyc lotzJamesl rosenbergClaire acevedoAerospace engineeringDepartment of orthopaedic surgeryNational institutes of healthUniversity of californiaDepartment of materials scienceResearch allocation committeeLawrence berkeley national laboratory

Type 2 Diabetes Changes Vertebral Disc Behavior

Type 2 Diabetes Changes Vertebral Disc Behavior
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San franciscoUnited statesLawrence berkeley laboratoryUniversity of california san diegoUniversity of california san franciscoClaire acevedoJeffreyc lotzJamesl rosenbergResearch allocation committeeUniversity of californiaUniversity of utahJamesl graham department of molecular biosciencesLawrence berkeley national laboratoryRoberto ritchie materials science divisionNational institutes of healthDepartment of orthopaedic surgery

Type 2 diabetes alters the behavior of discs

Type 2 diabetes alters the behavior of discs in the vertebral column, making them stiffer, and also causes the discs to change shape earlier than normal. As a result, the disc’s ability to withstand pressure is compromised. This is one of the findings of a new study in rodents from a team of engineers and physicians from the University of California San Diego, UC Davis, UCSF and the University of Utah.   

University of california san diegoUnited statesUniversity of california davisSan franciscoUniversity of california san franciscoLawrence berkeley laboratoryJamesl rosenbergClaire acevedoRoberto ritchieJeffreyc lotzMaterials science divisionTamaran alliston department of orthopaedic surgeryDepartment of nutritionDepartment of materials scienceUniversity of californiaJamesl graham department of molecular biosciences