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Study describes cardiovascular effects of grape seed extract Supplementation with grape seed extract can significantly modulated blood pressure, especially in men, and may also help to reduce the perception of stress, according to a new RCT.
Enovita, Indena s standardised grape seed extract (GSEe) from Vitis vinifera L. seeds, has previously been found to produce beneficial cardiovascular effects.
The current study aimed to discover the mechanism of action behind this benefit with an in vitro experiment using human umbilical vein endothelial cells (HUVEC).
The results suggested GSEe lead to a significant reduction of the adhesion molecules linked to inflammatory processes in endothelial cells (sICAM, sVCAM, and endothelin-1).