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Better designed vaccines for insect-spread viruses like dengue and Zika are likely after researchers discovered models of immature flavivirus particles were originally misinterpreted.
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IMAGE: Cryo-electron microscopy reconstruction of Binjari virus. The projecting spikes are a typical feature of immature flaviviruses such as dengue virus but reveal an unexpected organization. view more
Credit: Associate Professor Fasseli Coulibaly
Better designed vaccines for insect-spread viruses like dengue and Zika are likely after researchers discovered models of immature flavivirus particles were originally misinterpreted.
Researchers from The University of Queensland and Monash University have now determined the first complete 3D molecular structure of the immature flavivirus, revealing an unexpected organisation.
UQ researcher Associate Professor Daniel Watterson said the team was studying the insect-specific Binjari virus when they made the discovery.
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