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Workshop on capacity building in marine fish taxonomy concludes

Workshop on capacity building in marine fish taxonomy concludes
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Development of a target-capture NGS assay for use in molecular-based research of myeloid measurable residual disease

In this poster, Oxford Gene Technology (OGT) highlights the increasing role of molecular methods, specifically next-generation sequencing (NGS), in detecting measurable residual disease (MRD) in conditions like acute myeloid leukemia (AML). While real-time qPCR (RQ-PCR) and digital droplet PCR (ddPCR) are highly sensitive, they have limitations in detecting multiple targets in a single assay. NGS overcomes this limitation by allowing the evaluation of many genes and variant types in a single ass

How female scientists are advancing modern science

Frontiers | Seasonality in Environmental Conditions Drive Variation in Plankton Communities in a Shallow Tropical Lake

Factors influencing the spatio-temporal dynamics of plankton communities in small tropical lakes are not well understood. This study assessed plankton communities in response to spatial and seasonal (wet vs dry seasons) changes in environmental variables in Lake Kanyaboli, a small satellite lake on the northern shores of Lake Victoria, Kenya. Water quality variables, including pH, conductivity (EC), dissolved oxygen (DO), temperature, Secchi depth (SD), nitrates (NO3-), nitrites (NO2-), ammonium (NH4+), soluble reactive phosphorus (SRP), total nitrogen (TN), total phosphorus (TP), and chlorophyll-a (Chl-a), were monitored monthly at six sites spread throughout the lake for one year. Phytoplankton and zooplankton samples were collected and analyzed for taxon composition and abundance. Two-way ANOVA showed no significant interaction between site and season for all variables, except Chl-a. A t-test showed significant seasonal differences in SD, DO, NH4+, NO3-, NO2- and TN. Thirty phytopla

Molecular methods for pathogenic bacteria detection and recent advance by Shuxin Zhang, Xuan Li et al

With increasing concerns about public health and the development of molecular tech-niques, new detection tools and the combination of existing approaches have increased the abilities of pathogenic bacteria monitoring by exploring new biomarkers, increasing the sensitivity and ac-curacy of detection, quantification, and analyzing various genes such as functional genes and anti-microbial resistance genes (ARG). Molecular methods are gradually emerging as the most popular detection approach for pathogens, in addition to the conventional culture-based plate enumeration methods. The analysis of pathogens in wastewater and the back-estimation of infections in the com-munity, also known as wastewater-based epidemiology (WBE), is an emerging methodology and has a great potential to supplement current surveillance systems for the monitoring of infectious diseases and the early warning of outbreaks. However, as a complex matrix, wastewater largely challenges the analytical performance of molecul

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