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Secret genetic switch in zebrafish key to heart regeneration
Scientists have discovered a critical new gene in zebrafish that helps them repair damaged heart muscle.
Researchers at the Victor Chang Cardiac Research Institute (VCCRI) and UNSW Sydney have identified a genetic switch in zebrafish that turns on cells, allowing them to divide and multiply after a heart attack and resulting in the complete regeneration and healing of damaged heart muscle in these fish.
It’s already known that zebrafish can heal their own hearts, but how they performed this incredible feat remained unknown until now. In research published this month in Science, the team drilled down into a critical gene known as Klf1 that previously had only been identified in red blood cells. For the first time they discovered it played a vital role in healing damaged hearts.
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Victor Chang Cardiac Research Institute
Scientists at the Victor Chang Cardiac Research Institute have discovered a critical new gene that it is hoped could help human hearts repair damaged heart muscle after a heart attack.
Researchers have identified a genetic switch in zebrafish that turns on cells allowing them to divide and multiply after a heart attack, resulting in the complete regeneration and healing of damaged heart muscle in these fish.
It’s already known that zebrafish can heal their own hearts, but how they performed this incredible feat remained unknown, until now. In research recently published in the prestigious journal, Science, the team at the Institute drilled down into a critical gene known as Klf1 that previously had only been identified in red blood cells. For the first time they discovered it plays a vital role in healing damaged hearts.
Credit: Victo Chang Cardiac Research Institute
Scientists at the Victor Chang Cardiac Research Institute in Sydney have discovered a critical new gene that it is hoped could help human hearts repair damaged heart muscle after a heart attack.
Researchers have identified a genetic switch in zebrafish that turns on cells allowing them to divide and multiply after a heart attack, resulting in the complete regeneration and healing of damaged heart muscle in these fish.
It s already known that zebrafish can heal their own hearts, but how they performed this incredible feat remained unknown, until now. In research recently published in the prestigious journal,