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Proximal sciatic nerve block reduced pain after MPFL reconstruction in pediatric patients

Results showed the addition of a single-injection proximal sciatic nerve block to an adductor canal block significantly reduced pain and opioid requirements in pediatric patients undergoing medial patellofemoral ligament reconstruction.Researchers performed a retrospective cohort study on 144 pediatric patients who underwent (MPFL reconstruction with peripheral nerve blockade for postoperative

Anxiety, depression common at follow-up after differentiated thyroid cancer

More than one-third of patients treated for differentiated thyroid cancer reported elevated anxiety and more than 15% reported a high level of depression at an annual follow-up, according to study findings published in Thyroid.In an analysis of data from more than 600 survivors of differentiated thyroid cancer at a clinic in Germany, permanent hypoparathyroidism was a predictor for high anxiety

Greater IOP reduction achieved with once-daily vs twice-daily fixed combination drops

Once-daily fixed combination bimatoprost, timolol and brimonidine more effectively reduced peak IOP compared with a twice-daily regimen in patients with primary open-angle glaucoma, according to a study in the Journal of Glaucoma.

Electroconvulsive therapy effective for improving symptoms of mania

Electroconvulsive therapy was associated with improvement of symptoms in those with mania, with higher response rates in those more seriously ill and without comorbid anxiety or obsessive-compulsive disorder, per a recently published study.“Most guidelines recommend electroconvulsive therapy (ECT) as a second-line treatment for mania,” Katarzyna Popiolek, MD, of the University Health

Paclitaxel induction chemotherapy regimen more effective in nasopharyngeal carcinoma

Induction chemotherapy with paclitaxel, cisplatin and capecitabine vs. cisplatin and fluorouracil improved failure-free survival among patients with advanced nasopharyngeal carcinoma, according to a study published in JAMA Oncology.Results of the randomized, open-label, phase 3 trial also showed the paclitaxel combination did not result in a higher rate of serious adverse events, researchers

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