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FDA expands Breyanzi approval for relapsed or refractory large B-cell lymphoma

The FDA approved lisocabtagene maraleucel for treatment of adults with relapsed or refractory large B-cell lymphoma after one prior therapy.

Molecular signature-assisted drug selection may improve results in rheumatoid arthritis

Molecular signature response classifier-assisted rheumatoid arthritis treatment selection may improve real-world results in patients with rheumatoid arthritis, according to data published in Expert Opinion on Biological Therapy. “This study reports the second interim analysis of the [Accelerate Information of Molecular Signatures (AIMS)] real-world study evaluating the clinical utility of

FDA grants fast track designation to PDS0101 for head and neck cancer subset

The FDA granted fast track designation to PDS0101 for treatment of certain patients with head and neck cancer.The designation applies to use of the agent in combination with pembrolizumab (Keytruda, Merck) by patients with recurrent or metastatic HPV16-positive disease.

Health-related quality of life worse in NAFLD patients compared with general population

LONDON — Patients with nonalcoholic fatty liver disease had worse health-related quality of life, regardless of fibrosis stage, compared with the general population, according to research presented at the International Liver Congress. “Health-related quality of life has been shown to be impaired in NAFLD patients and potentially associated with fibrosis severity, obesity or other

Gender-Equity Model for Liver Allocation more accurately predicts mortality vs MELD

LONDON — The Gender-Equity Model for Liver Allocation and its sodium-corrected variant were better predictors of mortality or delisting in patients awaiting liver transplantation and may correct gender disparities, according to research. “The odds of delisting for sickness in women are 30% higher than in men, and this may have something to do with serum creatinine,” Manuel

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