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Patients with history of autoimmune disease have fewer AAV relapses

Patients with ANCA-associated vasculitis who have a history of autoimmune disease prior to diagnosis may have fewer relapses following remission, according to data published in Clinical and Experimental Rheumatology.

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Novel agent demonstrated tolerability, clinical response in patients with advanced NSCLC

For patients with advanced non-small cell lung cancer who showed an inadequate response to front-line immunotherapy checkpoint inhibitors and chemotherapy, the addition of CAN-2409 was well-tolerated. The preliminary clinical data of CAN-2409, a replication-deficient adenoviral gene construct that delivers the thymidine kinase gene, was presented at ASCO Annual Meeting.

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More data needed on sex, gender differences in stroke treatment, outcomes

Endovascular therapy is now a standard treatment for select patients with severe ischemic stroke to improve the likelihood of functional recovery; yet there remains a paucity of research on outcomes by sex and gender.The American Heart Association in June published a scientific statement on sex- and gender-related differences in endovascular stroke treatment in Stroke. The statement

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Local infiltration, interscalene block yield similar analgesia after shoulder arthroplasty

Despite higher pain scores at 8 hours postoperatively and increased opioid use, local infiltration analgesia was less costly and yielded similar pain scores at 24 hours after shoulder arthroplasty compared with an interscalene block.In a level-1, prospective randomized trial, Michael Ewing, MD, and colleagues from the University of Missouri compared outcomes between 37 patients who underwent

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FDA grants priority review to mosunetuzumab for relapsed or refractory follicular lymphoma

The FDA granted priority review to mosunetuzumab for treatment of certain patients with relapsed or refractory follicular lymphoma.The designation applies to use of the agent by adults who received at least two prior systemic therapies.

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