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Greater IOP reduction achieved with once-daily vs. twice-daily fixed combination drops

Once-daily fixed combination bimatoprost, timolol and brimonidine more effectively reduced peak IOP compared with a twice-daily regimen in patients with primary open-angle glaucoma, according to a study in the Journal of Glaucoma.

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Electroconvulsive therapy effective for improving symptoms of mania

Electroconvulsive therapy was associated with improvement of symptoms in those with mania, with higher response rates in those more seriously ill and without comorbid anxiety or obsessive-compulsive disorder, per a recently published study.“Most guidelines recommend electroconvulsive therapy (ECT) as a second-line treatment for mania,” Katarzyna Popiolek, MD, of the University Health

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Paclitaxel induction chemotherapy regimen more effective in nasopharyngeal carcinoma

Induction chemotherapy with paclitaxel, cisplatin and capecitabine vs. cisplatin and fluorouracil improved failure-free survival among patients with advanced nasopharyngeal carcinoma, according to a study published in JAMA Oncology.Results of the randomized, open-label, phase 3 trial also showed the paclitaxel combination did not result in a higher rate of serious adverse events, researchers

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Historical 'redlining' practices associated with worse cardiometabolic disease

Historical housing discriminatory practices are associated with modern-day cardiometabolic disease and risk factors years after such practices were outlawed, according to an analysis of census-level data.In a cross-sectional study, researchers found that “redlining” practices that graded neighborhoods according to perceived investment risk was associated with rates of CAD, chronic

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EMS agency practices affect out-of-hospital cardiac arrest survival rates

Differences in emergency medical service agency resuscitation practices may partly account for widely varying out-of-hospital cardiac arrest survival rates, researchers reported in Circulation: Cardiovascular Quality and Outcomes.“Our work highlights how important it is for emergency medical service agencies to review their resuscitation performance, and all related practices, to evaluate

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