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Novel PARP1 Inhibitor Shows Promise in Breast Cancer

The drug had favorable safety compared with first-generation PARP inhibitors in phase I/II study

United statesNew havenMike bassettTimothy yapPatricia lorussoAmerican association for cancer researchYale school of medicineUniversity of texas md anderson cancer centerCancer centerAmerican associationCancer researchYale school

Most Cancer Drugs Granted Accelerated Approval Fail Confirmatory Trials

Only 43% showed clinical benefit within 5 years

United statesEdward scheffer cliffShivaani kummarMike bassettAmerican association for cancer researchOregon health science university in portlandHarvard medical schoolAmerican associationCancer researchOregon healthScience university

Can Late-Stage Cancer Incidence Serve as an Endpoint for Screening Trials?

Study shows it may be an alternative to cancer-specific mortality for some cancers, but not all

United statesPeterb bachMike bassettHilarya robbinsAmerican association for cancer researchInternational agencyAmerican associationCancer researchNorth america

PSA and Biomarker Testing Plus MRI Appears to Improve Prostate Cancer Screening

Early results suggest approach reduces overdiagnosis while better detecting high-grade cancer

United statesVanderbilt universityMike bassettAnssi auvinenJeffreyj tosoianTampere universityVanderbilt university medical centerFinnish proscreenEuropean randomized studyProstate cancer

More Bird Flu Spread; FDA to Allow Gay Men to Donate Sperm; Oatzempic Trend

Health news and commentary from around the Web gathered by <em>MedPage Today</em> staff

United statesNew yorkUnited kingdomNew mexicoJerome adamsKristin lyerlyMike bassettBristol myers squibbWashington postNew york timesWorld organisation for animal healthHealth newsWorld organisationAnimal healthWall street journalDaily mail

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