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Study shines light on partial endothelial-to-mesenchymal transition in the tumor microenvironment

Endothelial-mesenchymal transition (EndoMT, also termed as EndMT), a biological process resulting in the formation of mesenchymal (or lineage-committed) phenotypes from endothelial cells (lining blood vessels), plays a crucial role in tumor progression.

Exploring Endothelial Cell Transformation in Cancer Progression

Exploring Endothelial Cell Transformation in Cancer Progression
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Japan s middle class being gutted as salaries fall

Japan s middle class being gutted as salaries fall
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Unique inhibitory protein may suppress the formation of cancer cells

Unique inhibitory protein may suppress the formation of cancer cells Researchers from Tokyo Medical and Dental University (TMDU) identify a novel role for a protein, vasohibin-1, in preventing cancer cells from spreading Cancer often becomes more difficult to treat and has a poorer prognosis when it spreads throughout the body. This process, called metastasis, is promoted by various cellular events not only become uncontrolled via mutations in cancerous cells, but also by the effects from many types of cells surrounding cancer. One such event is tumor angiogenesis - the abnormal development of new blood vessels in near solid cancers, causing cancer gets worth. Now, researchers at Tokyo Medical and Dental University (TMDU) have recently discovered a unique inhibitory function of a protein that may help suppress the formation of these tumor vessels in cancer tumors.

Hinder handing the message -- stopping tumors from creating new blood vessels

 E-Mail IMAGE: VASH1 exerts anti-angiogenic effects through the inhibition of receptor endocytosis by ?Y-tubulin increases. VEGF and FGF2 induce endocytosis of their own receptors, VEGFR2 and FGFR1, respectively, along MTs. This is. view more  Credit: Department of Biochemistry,TMDU Researchers from Tokyo Medical and Dental University (TMDU) identify a novel role for a protein, vasohibin-1, in preventing cancer cells from spreading Tokyo, Japan - Cancer often becomes more difficult to treat and has a poorer prognosis when it spreads throughout the body. This process, called metastasis, is promoted by various cellular events not only become uncontrolled via mutations in cancerous cells, but also by the effects from many types of cells surrounding cancer. One such event is tumor angiogenesis - the abnormal development of new blood vessels in near solid cancers, causing cancer gets worth. Now, researchers at Tokyo Medical and Dental University (TMDU) have recently discove

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