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Molecular Link Discovered: Johns Hopkins Medicine Scientists Connect Wet and Dry Macular Degeneration

In the December issue of the Proceedings of the National Academy of Sciences, Wilmer Eye Institute researchers at Johns Hopkins Medicine have found how a molecular pathway involving oxidative stress, or an imbalance of molecular oxygen in cells, an

United statesSilvia aparicio domingoAkrit sodhiLyu qinMurilo rodriguesYueqi niuRakesh chopdeHaley megarityCharles eberhardtTimothy domashevichMiguel flores bellverMonika deshpandeChuanya guoSavalan babapoor farrokhranSilvia montanerProceedings of the national academy sciences

Association for Research in Vision and Ophthalmology (ARVO)

Association for Research in Vision and Ophthalmology (ARVO)News, press releases, and expert sources for journalists in science, medicine & business

United kingdomDavidl epsteinPatrick yuMiguel flores bellverBertm glaserPatriciaa damoreAssociation for researchPfizer ophthalmics carl camras translational research awardJerusalem eye hospital groupPoint of view foundation fundaciMd award for innovative research in retinaPhd university of cambridgeChampalimaud visionNew orleansPatrick yu wai manSallmann clinician scientist

New age-related macular degeneration study uses light-sensitive retinal organoids

New age-related macular degeneration study uses light-sensitive retinal organoids
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United statesValeria canto solerMiguel flores bellverSilvia aparicio domingoTimothy domashevichJohns hopkinsSavalan babapoor farrokhranCu department of ophthalmologyUniversity of colorado school medicineOcular stem cell researchJohns hopkins universityProceedings of the national academy sciencesColorado schoolNational academyDoni solich family chairOcular stem cell

CU s CellSight contributes light-sensitive re

<p>To better understand how oxidative stress affects the progression of age-related macular degeneration, researchers are using “mini retinas” and retinal pigment epithelium monolayers derived from stem cells developed by Department of Ophthalmology faculty.</p>

United statesTimothy domashevichJohns hopkinsMiguel flores bellverSilvia aparicio domingoValeria canto solerUniversity of colorado school medicineJohns hopkins universityCu department of ophthalmologyProceedings of the national academy sciencesOcular stem cell researchColorado schoolNational academyDoni solich family chairOcular stem cell

Experimental drug inhibits or prevents diabetic eye disease: In mice and human cell models, the drug 32-134D lowered protein levels known to contribute to diabetic macular edema and diabetic retinopathy

Researchers say they have evidence that an experimental drug may prevent or slow vision loss in people with diabetes. The results are from a study that used mouse as well as human retinal organoids and eye cell lines.

Johns hopkins universityUnited statesUniversity of marylandSybilb harrington steinKathleen jeeJaron sanchezNicole andersJing zhangMiguel flores bellverAumreetam dinabandhuBranna irving sisenweinMonika deshpandeYousang hwandChuanyu guoShaima salmanPuchner applewhite