Popular Blood Thinner Linked to Higher Risk of Bleeding Events
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Popular blood thinner associated with higher risk of bleeding complications
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Implications of Adding Aspirin to DOAC Without Clear Indication
Apr 28, 2021
Citation: Concomitant use of aspirin and a DOAC is common among patients without an indication for DAPT. Aspirin and DOAC are associated with higher rates of bleeding and hospitalization compared to DOAC alone.
No difference in thrombosis rates was observed for patients using aspirin plus a DOAC compared to a DOAC alone.
Study Questions:
Among patients taking a direct oral anticoagulant (DOAC) for atrial fibrillation (AF) and/or venous thromboembolism (VTE), what are the outcomes following concurrent aspirin use?
Methods:
Data from the Michigan Anticoagulation Quality Improvement Initiative (MAQI
2) were used for the present analysis. Four anticoagulation clinics in Michigan provided data from January 2015 to December 2019 on eligible adults undergoing treatment with a DOAC for AF or VTE, without a recent myocardial infarction (MI), history of heart valve replacement, and with ≥3 months of foll