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First in-depth study of Omicron variant offers mixed bag: Could booster shots be the key?

First in-depth study of Omicron variant offers mixed bag: Could booster shots be the key?
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South africaUnited statesJohnp mooreCarolyny johnsonBenjamin neumanWilliam hanageJoel achenbachMichelc nussenzweigDavidr martinezTexasam universityRockefeller universityPublic healthNorth carolinaGillings schoolGlobal public healthWeill cornell

First lab results show omicron has much more extensive escape from antibodies than previous variants

The study also suggests that booster shots could be key in the battle with the variant.

South africaUnited statesJohnp mooreBenjamin neumanWilliam hanageMichelc nussenzweigDavidr martinezTexasam universityRockefeller universityPublic healthNorth carolinaGillings schoolGlobal public healthWeill cornell

First lab results show omicron variant did not escape antibodies completely

The first laboratory study testing the omicron variant of the coronavirus against the Pfizer-BioNTech vaccine shows the variant has significant, but not total, ability to evade the virus-fighting antibodies that are a key line of defense.

South africaUnited statesJohnp mooreBenjamin neumanWilliam hanageMichelc nussenzweigDavidr martinezTexasam universityRockefeller universityPublic healthNorth carolina gillings schoolGlobal public healthWeill cornell

First lab results show omicron has much more extensive escape from antibodies than previous variants

The study is one of the first clues that will help inform whether there needs to be an omicron-specific shot.

New yorkUnited statesSouth africaRockefeller universityKwazulu natalEastern capeCarolyny johnsonWilliam hanageJohnp mooreBenjamin neumanJoao silvaJoel achenbachDavidr martinezMichelc nussenzweigNatal researchNew york times

Researchers find the differences in COVID antibody responses to vaccination and natural infection

Hope for a future without fear of COVID-19 comes down to circulating antibodies and memory B cells. Unlike circulating antibodies, which peak soon after vaccination or infection only to fade a few months later, memory B cells can stick around to prevent severe disease for decades. And they evolve over time, learning to produce successively more potent "memory antibodies" that are better at neutralizing the virus and more capable of adapting to variants.

Michelc nussenzweigRalphm steinmanEmily hendersonZanvila cohnLaboratory of molecular immunologyRockefeller universityMolecular immunologyB cellImmune system