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ASCO GU 2021: Clinical Conundrums of Genomically Driven Prostate Cancer

Published 12 February 2021 (UroToday.com) The case presented was that of a 54-year-old man with an extensive family history of cancer. His mother died from ovarian cancer, his father had prostate cancer and died of colon cancer, his brother developed kidney and prostate cancer, and his sister had breast and ovarian cancer. The patient had germline testing, which revealed a heterozygous BRCA1 c.1961delA known pathogenic frameshift mutation that leads to a truncated or absent protein. The patient’s medical history was also notable for a pT1 seminoma treated with orchiectomy and radiotherapy (likely unrelated to the BRCA1 alteration) and a recent squamous cell of unknown primary in an inguinal node that was detected during his prostate cancer workup. This was treated with radiotherapy and concurrent 5FU/cisplatin. 

Brown: SJU s Jesuit academic freedom and the culture of encounter of Pope Francis | Opinion

In the midst of final exam week and the COVID-19 pandemic, Saint Joseph’s University held true to its promise of presenting the “Reverend Donald I. MacLean Chair” Fall 2020 Lecture for students, faculty, staff, and community members. Well-attended virtually with over fifty guests, the webinar featured the Academic Year 2020-2021 MacLean Chair Dr. Andreas Gösele, S.J. whose areas of expertise include political and social philosophy, social and environmental ethics, logic, and the foundational and philosophical issues in economics. The Donald I. MacLean, S.J. Chair is held by members of the Society of Jesus who are accomplished teachers and scholars in the Arts and Sciences. The Chair is named in honor of the University’s 24th president.

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