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And butter. Were talking about her and oeismt ceo blunders. Tyler is out and simon is back with me. Hi. Good afternoon. We start with something on this show 24 hours ago it was a big headsup on a stock that could have been about to make a very big move. A biostock that many analysts will quickly double, vertex pharmaceutical reporting data. And move it did. Vertex shares up big on news that the drug combo is an effective fighter on cystic fibrosis. Its up, up and away today. Our own meg tirrell fresh from doing a lap of honor around the headquarters joins us with more. They met and exceeded the streets expect aations this co bock improved function. We took a look at how they work. Cystic fibrosis is caused by mutations to a gene known as cftr. When the gene is defective, the protein it creates cant help fluoride escape the cell. That hampers the movement of fluid across the cell wall and leads to product of thick mucus. The first medicine cass kaledyco. Which allows chloride to pass th

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