Gene variant influences blood clot risk in severe Covid
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Genetic risk factors for severe COVID-19 identified
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Uppsala University
In a new study, Uppsala researchers followed the progress of 111 patients with COVID-19 being treated in intensive care.
Photograph: Uppsala University Hospital
In a new study, Uppsala researchers have found that two biomarkers in blood are more common in severely ills COVID-19 patients that develop muscle weakness during intensive care. This finding can allow preventive treatment to be given earlier.
“Our results show that the levels of two specific biomarkers in blood, neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAp), which signal damage to the nervous system, were higher at an early stage in the group of COVID-19 patients receiving intensive care and that developed muscle weakness. These patients also had longer care times, higher risk of blood clots and greater need of respirator support over a long period. The hope is that the new findings can lead to at-risk patients being identified earlier and that they can more quickly recei