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Melatonin could act as barrier against COVID-19 infection

Melatonin could act as barrier against COVID-19 infection
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Regina pekelmann markusMelatonin researchProfessor regina pekelmann markus

Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2

Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2 Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2, preventing expression of genes that encode proteins in cells such as resident macrophages in the nose and pulmonary alveoli, and epithelial cells lining the alveoli, all of which are entry points for the virus. The hormone, therefore, prevents infection of these cells by the virus and inhibits the immune response so that the virus remains in the respiratory tract for a few days, eventually leaving to find another host. The discovery by researchers at the University of São Paulo (USP), in Brazil, helps understand why some people are not infected or do not manifest symptoms of COVID-19 even when reliably diagnosed as carriers of the virus by RT-PCR. In addition, it offers the prospect of nasal administration of melatonin, in drops or as a spray, to prevent disease from developing in pre-symptomatic patients.

Marcos buckeridgeHelder nakayaRegina pekelmann markusEmily hendersonMelatonin researchInstitute of biosciencesJournal of pineal researchSchool of pharmaceutical sciencesPekelmann markusPrincipal investigatorPineal researchPharmaceutical sciencesGene expressionImmune responseSars cov 2வைத்திருப்பவர் நாகாய

Melatonin produced in lungs can prevent Covid-19 infection: Study

January 28, 2021 Melatonin encodes proteins in cells to prevent virus entry Melatonin synthesised in the lungs acts as a barrier against Covid-19 infection. This also prevents the expression of genes that are entry points for the virus, researchers at the University of São Paulo (USP) stated in a study. The study, published in the journal Melatonin Research, found that melatonin encodes proteins in cells such as resident macrophages in the nose and pulmonary alveoli, and epithelial cells lining the alveoli, to prevent virus entry. The hormone, therefore, prevents infection of these cells by the virus and inhibits the immune response so that the virus remains in the respiratory tract for a few days. The virus eventually leaves to find another host.

Regina pekelmann markusMelatonin researchInstitute of biosciencesPekelmann markusநிறுவனம் ஆஃப் உயிர் அறிவியல்

Melatonin produced in the lungs prevents infection by novel coronavirus

E-Mail IMAGE: The hormone acts as a barrier against SARS-CoV-2, blocking the expression of genes that encode proteins in cells serving as viral entry points, according to a study by researchers at. view more Credit: NIAD/NIH By Elton Alisson | Agência FAPESP - Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2, preventing expression of genes that encode proteins in cells such as resident macrophages in the nose and pulmonary alveoli, and epithelial cells lining the alveoli, all of which are entry points for the virus. The hormone, therefore, prevents infection of these cells by the virus and inhibits the immune response so that the virus remains in the respiratory tract for a few days, eventually leaving to find another host.

Elton alissonMarcos buckeridgeHelder nakayaRegina pekelmann markusMelatonin researchInstitute of biosciencesJournal of pineal researchPaulo research foundationSchool of pharmaceutical sciencesPekelmann markusPineal researchPharmaceutical sciencesஎல்டன் அலிசன்வைத்திருப்பவர் நாகாயநிறுவனம் ஆஃப் உயிர் அறிவியல்பாலொ ஆராய்ச்சி அடித்தளம்