Parkinson's disease is best-known as a disorder of movement. Patients often experience tremors, loss of balance, and difficulty initiating movement. The disease also has lesser-known symptoms that are nonmotor, including depression.
Neurons in the parafascicular thalamus project to three different parts of the basal ganglia. Targeting these circuits could be a new target for treating motor dysfunction and depression associated with Parkinson's disease.
MIT neuroscientists identified three circuits in the thalamus that influence the development of motor and nonmotor symptoms of Parkinson’s disease. And by manipulating these circuits, they could reverse Parkinson’s symptoms in mice.
Three distinct brain circuits in thalamus contribute to Parkinson s symptoms miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.