In findings with implications for future therapies in chronic kidney disease, mouse studies show a protective effect of glucagon receptor signaling in the kidney.
Glucagon, a hormone best known for promoting blood sugar production in the liver, also appears to play a key role in maintaining kidney health. When UT Southwes
Study shows glucagon is key for kidney health medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.
Glucagon, a hormone best known for promoting blood sugar production in the liver, also appears to play a key role in maintaining kidney health. When UT Southwes
Could transforming alpha cells into beta cells treat diabetes?
Written by James Kingsland on March 4, 2021 Fact checked by Rita Ponce, Ph.D.
New research in mice suggests a novel way to treat both forms of diabetes. 1130945222 Tom Werner/Getty Images
Scientists have used synthetic antibodies to block cell receptors in the liver that normally bind to glucagon, a hormone involved in increasing the amount of glucose in the blood.
The antibodies restored normal blood glucose levels in three different mouse models of diabetes.
The treatment partly worked by transforming alpha cells in the pancreas into insulin-producing beta cells.
The researchers believe that the same approach could treat type 1 and type 2 diabetes in people.