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Anatomical barriers shield brain from SARS-CoV-2 invasion at vulnerable interfaces

Anatomical barriers shield brain from SARS-CoV-2 invasion at vulnerable interfaces
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Region flamandeBruxelles capitaleLaura van gervenPeter mombaertsMax planck research unit for neurogeneticsUniversity hospitals leuvenMax planck research unitAdds laura van gerven

COVID loss of smell is connected to cells scientists barely understand

A new study, which is based on samples from deceased COVID patients, found no evidence of a pathway for the coronavirus to the brain – but did find that little-known sustentacular cells are the main target

Rio de janeiroEstado do rioUnited kingdomRegion flamandeHebrew universityLaura van gervenRandy wongMona khanPeter mombaertsBoris johnsonMax planck research unit for neurogeneticsForum infectious diseasesUniversity hospitals leuvenDepartment of biochemistryMax planck research unitUniversity hospitals

Scientists find infection of sustentacular cells in the olfactory epithelium of COVID-19 patients

It is now widely known that COVID-19 is associated with the transient or long-term loss of olfaction (the sense of smell) but the mechanisms remain obscure.

Region flamandeUnited statesLaura van gervenMona khanPeter mombaertsEmily hendersonMax planck research unit for neurogeneticsUniversity hospitals leuvenNanostring technologies incMax planck research unitNanostring technologiesDigital spatial profilerArs cov 2

SARS-CoV-2 Does Not Infect Olfactory Neurons, Spatial Analysis Suggests

SARS-CoV-2 infects the sustentacular cells in the olfactory epithelium of COVID-19 patients, not nerve cells in the olfactory bulb.

Laura van gervenMona khanPeter mombaertsMax planck research unit for neurogeneticsMax planck research unitDigital spatial profilerNanostring technologies

Human brain cells not infected by Covid virus: Study

An international team of researchers has, in a new study, claimed that SARS-CoV-2, the virus that causes Covid-19, does not infect human brain cells, raising hopes that Covid-related damage to sense of smell may be more superficial than previously feared. The study, published in the journal Cell, showed that the virus infects sustentacular cells associated with structural

New yorkUnited statesZuid hollandColumbia universityStuart firesteinPeter mombaertsMax planck research unit for neurogeneticsErasmus university in rotterdamMax planck research unitDebby van rielErasmus universityCovid 19Ars cov 2Cience newsNew york

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