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Microbiome Perturbations in Male Mice Increase Offspring s Disease Risk

Microbiome Perturbations in Male Mice Increase Offspring s Disease Risk
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Baden wübergJamie hackettAyele denbobaPeer borkEuropean molecular biology laboratoryMax planck institute of immunobiologyMax planck instituteJessona sound

Cannibalism, barbed penises and a whole lot of venom: The 8 most brutal animal courtships

Cannibalism, barbed penises and a whole lot of venom: The 8 most brutal animal courtships
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Biophysics breakthroughs take centre stage at annual meeting – Physics World

Biophysics breakthroughs take centre stage at annual meeting – Physics World
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Research reveals clever dosage control mechanism of biallelic genes

Research reveals clever dosage control mechanism of biallelic genes
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Asifa akhtarSteffen dietzel wikipediaMeike wieseYidan sunMax planck institute of immunobiologyMax planck institute

Revisiting gene dosage

<p><strong>Researchers have uncovered a mechanism that safeguards the biallelic expression of haploinsufficient genes, shedding light on the importance of having two copies of each chromosome. A study by the lab of Asifa Akhtar identified the epigenetic regulator MSL2 an “anti-monoallelic” factor that maintains biallelic gene dosage. This discovery not only reveals a communication system between parental alleles but also points to potential therapeutic strategies for diseases associated with haploinsufficient genes.</strong></p>

Meike wieseAsifa akhtarYidan sunMethod of researchMax planck institute of immunobiologyMax planck institute