14 Sep 2021
Metabolic profiling of cell line collections has become an invaluable tool in the study of disease etiology, drug modes of action, and to select personalized treatments. However, large-scale in vitro dynamic metabolic profiling is limited by time-consuming sampling and complex measurement procedures. By combining an high-throughput metabolomics platform developed at the Institute of Molecular Systems Biology of ETH in Zurich with time-lapse microscopy, Dr. Mattia Zampieri has established a workflow for the large-scale metabolic profiling of adherent mammalian cells and the rapid measurement and analysis of drug-induced dynamic changes in intracellular metabolites.
In this webinar, Dr. Mattia Zampieri, junior PI at the institute, will illustrate how this technology enables them to study the role of aberrant transcriptional regulation in mediating cancer metabolic rewiring and how it can be applied to reveal drug mechanisms of action. This approach opens new opportunities
14 Sep 2021
Metabolic profiling of cell line collections has become an invaluable tool in the study of disease etiology, drug modes of action, and to select personalized treatments. However, large-scale in vitro dynamic metabolic profiling is limited by time-consuming sampling and complex measurement procedures. By combining an high-throughput metabolomics platform developed at the Institute of Molecular Systems Biology of ETH in Zurich with time-lapse microscopy, Dr. Mattia Zampieri has established a workflow for the large-scale metabolic profiling of adherent mammalian cells and the rapid measurement and analysis of drug-induced dynamic changes in intracellular metabolites.
In this webinar, Dr. Mattia Zampieri, junior PI at the institute, will illustrate how this technology enables them to study the role of aberrant transcriptional regulation in mediating cancer metabolic rewiring and how it can be applied to reveal drug mechanisms of action. This approach opens new opportunities
Top List: Access your free cancer and immunology resources ahead of the virtual summit
Explore topics from live-cell analysis,
in situ hybridization, cancer therapeutics, cell imaging, and much more
17 May 2021
To help you prepare for the upcoming SelectScience
® Virtual Cancer and Immunology Research Summit launching on Tuesday, May 11, we ve pulled together a selection of the latest resources, methods, and interviews that are progressing the fields of cancer and immunology research, covering topics from next-generation cancer treatments to
in situ hybridization and live-cell imaging.
Next-generation cancer treatment
Watch this video to find out why biomarkers are not only providing novel insights into the biology of cancer but ultimately enabling a new level of patient stratification. This allows the most effective treatment to be used for any given cancer leading to significantly improved outcomes for patients.
Discover the scientists advancing cancer research on The Scientists Channel
Hear from cancer research experts such as Dr. Aleksandra Dukic and Dr. Gerhard Bauer on The Scientists Channel
Limiting glioblastoma invasion in the brain: Dr. Aleksandra Dukic, postdoctoral researcher at the Institute for Cancer Research, Oslo University Hospital, discusses how she is investigating novel gap junction inhibitors for use in sensitizing glioblastoma cells to chemotherapy.
The incubation technology accelerating CAR-T cell therapy development: Dr. Gerhard Bauer, Professor of Hematology and Oncology and Director of the GMP lab at the UC Davis Institute, reveals the secrets to success in his work on the production of CAR-T cells.
Discover the scientists advancing cancer research on The Scientists Channel
Hear from cancer research experts such as Dr. Aleksandra Dukic and Dr. Gerhard Bauer on The Scientists Channel
Limiting glioblastoma invasion in the brain: Dr. Aleksandra Dukic, postdoctoral researcher at the Institute for Cancer Research, Oslo University Hospital, discusses how she is investigating novel gap junction inhibitors for use in sensitizing glioblastoma cells to chemotherapy.
The incubation technology accelerating CAR-T cell therapy development: Dr. Gerhard Bauer, Professor of Hematology and Oncology and Director of the GMP lab at the UC Davis Institute, reveals the secrets to success in his work on the production of CAR-T cells.