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Federal Judge Halts Arizona Ban on Filming Police Within 8 Feet

PIGSKIN PREVIEW 2022: Legacy Charter | West Orange Times & Observer | West Orange Times & Windermere Observer

The Eagles' first game will take place at 7 p.m., Aug. 19, against Somerset Academy.

Maldon Festival final weekend of music at St Mary s Church | Maldon and Burnham Standard

Stephen Schroder Joins JAM FINTOP to Support JAM FINTOP Blockchain Fund

NEW YORK, NY & NASHVILLE, TN (PRWEB) May 16, 2022 JAM FINTOP announced the hiring of Stephen Schroder to help source, diligence and monitor companies for

Frontiers | Stiffening of Circumferential F-Actin Bands Correlates With Regenerative Failure and May Act as a Biomechanical Brake in the Mammalian Inner Ear

The loss of inner ear hair cells causes permanent hearing and balance deficits in humans and other mammals, but nonmammals recover after supporting cells (SCs) divide and replace hair cells. The proliferative capacity of mammalian SCs declines as exceptionally thick circumferential F-actin bands develop at their adherens junctions. We hypothesized that the reinforced junctions were limiting regenerative responses of mammalian SCs by impeding changes in cell shape and epithelial tension. Using micropipette aspiration and atomic force microscopy, we measured mechanical properties of utricles from mice and chickens. Our data show that the epithelial surface of the mouse utricle stiffens significantly during postnatal maturation. This stiffening correlates with and is dependent on the postnatal accumulation of F-actin and the cross-linker Alpha-Actinin-4 at SC-SC junctions. In chicken utricles, where SCs lack junctional reinforcement, the epithelial surface remains compliant. There, SCs un

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