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UK Researchers Develop Online Portal to Show How Biases in RNA Sequences Affect Gene Expression

A recent publication from researchers at the University of Kentucky explains the importance of identifying and understanding how differences between tissues and cells alter gene expression without changing the underlying genetic code. Introductory biology classes teach that DNA is transcribed into RNA, which is then translated into proteins. However, many cellular processes affect how quickly transcription and translation occur in a tissue or cell. Gene expression looks at the differences in RNA concentrations within a cell, and can help scientists know which genes are active within that tissue or cell.

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