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Researchers identify rescue mechanism that helps cells survive malfunctioning split

Masashi Yukawa & Takashi Toda, Hiroshima University Cells replicate their genetic material and divide into two identical clones, perpetuating life until they don’t. Some cells pause or are intentionally made to pause in the process. When the cell resumes division after such a pause, a displaced nucleus an essential part of cell survival can become caught in the fissure, splitting violently and killing both cells. But that is not always the case; some mutant cells can recover by pushing their nucleus to safety. Researchers from Hiroshima University in Japan are starting to understand how in the first step toward potential cell death rescue applications.

Researchers identify

Credit: Masashi Yukawa & Takashi Toda, Hiroshima University Cells replicate their genetic material and divide into two identical clones, perpetuating life until they don t. Some cells pause or are intentionally made to pause in the process. When the cell resumes division after such a pause, a displaced nucleus an essential part of cell survival can become caught in the fissure, splitting violently and killing both cells. But that is not always the case; some mutant cells can recover by pushing their nucleus to safety. Researchers from Hiroshima University in Japan are starting to understand how in the first step toward potential cell death rescue applications.

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