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Hold Off on HIIT for Patients with Heart Failure with Preserved EF

Feb 11, 2021 Stick to guideline-based physical activity for improving cardiorespiratory fitness, diastolic function High-intensity interval training (HIIT) is no better than moderate continuous training at improving peak oxygen consumption (VO 2) in patients with heart failure with preserved ejection fraction (HFpEF), although both did improve it, according to a recent study published in Further, neither exercise regimen was more effective at improving peak VO 2 compared with guideline-based physical activity, and neither brought about clinically relevant changes in cardiorespiratory fitness, diastolic function, or natriuretic peptide levels after 3 or 12 months when compared with guideline-recommended physical activity, Martin Halle, MD, of the Technical University of Munich, Munich, Germany, and fellow researchers with the OptimEx-Clin Study Group reported.

HIIT for HFpEF? Results Mixed in Exercise Trial

email article High-intensity interval training (HIIT) did not beat traditional exercise in raising exercise capacity for sedentary patients with heart failure with preserved ejection fraction (HFpEF), according to the OptimEx-Clin trial. HIIT and moderate continuous training groups yielded similar improvements in peak oxygen consumption (VO 2) from baseline to 3 months (+1.1 vs +1.6 mL/kg/min) both too modest to meet a prespecified minimal clinically-important threshold in comparison with controls (-0.6 mL/kg/min). Neither HIIT nor traditional exercise remained associated with improved exercise capacity at 12 months compared with controls, who got no supervised exercise training, only guideline-directed advice on physical activity, reported Martin Halle, MD, of the Technical University of Munich, Germany, and colleagues online in

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