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March 5, 2021 FDG-PET/MRI is a promising alternative to FDG-PET/CT for staging and gauging treatment response for Hodgkin lymphoma, with the benefit of less radiation to pediatric and adolescent patients, according to a study published online February 19 in the
FDG-PET/MRI achieved sensitivity and specificity greater than 95% for cancer detection and sensitivity of 83% and specificity of 100% in determining early postchemotherapy treatment response among 24 patients, essentially mirroring the proficiency of FDG-PET/CT. This prospective observational study demonstrates that FDG-PET/MRI is a promising alternative to FDG-PET/CT for staging and chemotherapy response assessment for pediatric [Hodgkin s] lymphoma, wrote the researchers, led by first author Dr. Martijn Verhagen, pediatric radiologist at University Medical Center Groningen, the Netherlands. By replacing FDG-PET/CT with FDG-PET/MRI, children with Hodgkin lymphoma will receive a lower cumulative radiation dose at st