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SHINE trial reveals risks of high blood sugar in post-thrombolysis stroke care

SHINE trial reveals risks of high blood sugar in post-thrombolysis stroke care
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Markr-conaway
Qi-pauls
Andrew-southerland
Ashleyc-bolte
Nicolea-chiota-mccollum
Stephana-mayer
Thomasp-bleck
University-of-virginia-health-system
School-of-medicine
Precision-health-for-populations
Stroke-hyperglycemia-insulin-network-effort
Department-of-neurology

FDA Panel Votes That Phase 3 PFS Data for Sotorasib in KRAS G12C+ Advanced NSCLC Cannot Be Reliably Interpreted

In a 10-to-2 vote, the FDA’s Oncologic Drugs Advisory Committee voted that the data for progression-free survival per blinded independent central review from the phase 3 CodeBreaK 200 trial evaluating sotorasib vs docetaxel for the treatment of patients with pretreated, locally advanced or metastatic KRAS G12C–mutated non–small cell lung cancer cannot be reliably interpreted.

Markr-conaway
Jorge-nieva
Ravia-madan
Jeevan-puthiamadathil
Division-of-translational-research
University-of-virginia-school-medicine
National-cancer-institute
Keck-school-of-medicine
Statistics-department-of-public-health-sciences
University-of-southern-california
Oncologic-drugs-advisory-committee
Drugs-advisory-committee

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