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IMAGE: A) Spatial organisation of the catalytic biostructures. B) and C) Detail of the two types of amino acids and their interactions. view more
Credit: IBB-UAB
Researchers at the UAB have designed minimalist biostructures that imitate natural enzymes, capable of carrying out two differentiated and reversibly regulated activities thanks to a unique combination of structural and functional properties. The strategy used opens the door to the creation of intelligent nanomaterials with tailor-made combinations of catalytic functions.
There is an increasing interest in synthetic systems that can execute bioinspired chemical reactions without requiring the complex structures that characterise enzymes in their components. One of the most explored approaches is the self-assembly of peptides - molecules smaller than proteins - due to their biocompatibility and how their structural and functional properties can be controlled.