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Unexpected Variation in Key RNA Gene

Although ribosomal RNA genes were thought to be similar among people, researchers have found that they differed significantly based upon a person’s geographic ancestry. Particularly high variations were found on a segment called 28S rRNA, an essential component of the protein-translating ribosome. While still too early to speculate what these variants mean, the fact that they are conserved by population means their retention is important.

Genome study reveals unexpected heterogeneity of human ribosomal RNA genes

A genome study undertaken by Johns Hopkins Kimmel Cancer Center researchers to look for variants in a gene considered a fundamental building block for microscopic structures that synthesize proteins took a surprising twist.

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