Rutgers will provide COVID antibody testing for more than 2,000 children as part of an initiative to determine the incidence of long-term COVID-19 in children.
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TB-causing bacteria remember prior stress, react quickly to new stress
HOUSTON – (Feb. 22, 2021) -Tuberculosis bacteria have evolved to remember stressful encounters and react quickly to future stress, according to a study by computational bioengineers at Rice University and infectious disease experts at Rutgers New Jersey Medical School (NJMS).
Oleg Igoshin (Photo by Jeff Fitlow/Rice University)
Published online in the open-access journal mSystems, the research identifies a genetic mechanism that allows the TB-causing bacterium, Mycobacterium tuberculosis, to respond to stress rapidly and in manner that is “history-dependent,” said corresponding author Oleg Igoshin, a professor of bioengineering at Rice.
Researchers have long suspected that the ability of TB bacteria to remain dormant, sometimes for decades, stems from their ability to behave based upon past experience.
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Rutgers researchers have been awarded $1.6 million from the National Institutes of Health in support of the creation of a national collaborative network seeking to identify risk and protective factors that may allow clinicians or public health professionals to predict which children are at greatest risk for serious illness from SARS-CoV-2 infection, the virus that causes COVID-19.
While children are less likely than adults to become severely ill, some develop severe acute respiratory illness; they also are susceptible to multisystem inflammatory syndrome of children (MIS-C), a critical illness that can occur several weeks after infection.
The two-year grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) of the NIH will support the development of a national network of networks, thus building an infrastructure that ensures that children from around the country can be a part of the study. The project is designed to incorpor