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UC San Francisco scientists have formed a research alliance with pharmaceutical firm Eli Lilly and Company aimed at better understanding autoimmune diseases and fostering the development of new therapies. Based on the innovative Immunoprofiler model launched at UCSF in 2017, the new initiative, called AutoImmunoprofiler, inherits the most successful aspects of its predecessor and adapts them to the study of autoimmunity.Â
Autoimmune diseases such as lupus, inflammatory bowel disease, and type 1 diabetes occur when the immune system attacks the bodyâs own tissues. While there are some therapies to treat symptoms of these conditions, the underlying causes are largely unknown. Â Â Â
Matthew âMaxâ Krummel, PhD
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Just over 200,000 Americans suffer from systemic lupus erythematosus, or SLE, a condition in which the body s immune system mistakenly attacks its own healthy tissues, especially joints and skin, a new study shows.
Led by a researcher at NYU Grossman School of the Medicine, the study provides the first national estimate of how widespread the autoimmune disease is since the U.S. Centers for Disease Control and Prevention (CDC) set up a half dozen state registries to track the illness more than a decade ago. SLE affects mostly women, can be fatal, and often involves debilitating flare-ups of fatigue and pain that keep nearly half of adult patients from working.