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Inflammatory Biomarker Tied to Mitochondrial Decline, Frailty

Inflammatory Biomarker Tied to Mitochondrial Decline, Frailty
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Caglar cosardereliogluCissy zhangAlessandra merino gomezConover talbotEanne leJeremy walstonHuanle yangLiliana floreaYuqiong wuCorina antonescuPeter abadirLolita nidadavoluJennifer fairmanTaylor boppRuth marx rattnerTu nguyen

New findings show mitochondrial DNA fragments in blood as important biomarkers for aging and inflammation: High levels of cell free DNA circulating in blood is further linked to chronic inflammation, a well-known risk factor for severe aging symptoms and frailty in older adults

New findings show mitochondrial DNA fragments in blood as important biomarkers for aging and inflammation: High levels of cell free DNA circulating in blood is further linked to chronic inflammation, a well-known risk factor for severe aging symptoms and frailty in older adults
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Johns hopkinsFrancine grodsteinLolita nidadavoluDavid bennettJeremy walstonYuqiong wuDanielle fegerPeter abadirAlden grossDiefei chenMinority aging research studyJohns hopkins university school of medicineAlzheimer disease centerNational institute on aging epidemiologyMargarett shock aging research foundationRush university

Circulating cell-free mitochondrial DNA could be useful biomarkers for aging and inflammation

In an eight-year study of more than 600 community-dwelling older adults, Johns Hopkins Medicine researchers say they have further linked levels of cell-free DNA (DNA fragments resulting from cell death) circulating in the blood to chronic inflammation and frailty.

Lolita nidadavoluFrancine grodsteinYuqiong wuAlden grossJohns hopkinsPeter abadirDavid bennettLily ramseyDiefei chenDanielle fegerJeremy walstonAlzheimer disease centerMinority aging research studyJohns hopkins university school of medicineRush universityNational institute on

Mitochondrial DNA Fragments in Blood as Biomarkers for Aging and Inflammation

Mitochondrial DNA Fragments in Blood as Biomarkers for Aging and Inflammation
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Johns hopkinsDavid bennettDanielle fegerAlden grossDiefei chenLolita nidadavoluPeter abadirYuqiong wuJeremy walstonFrancine grodsteinNational institute onRush universityMargarett shock aging research foundationAlzheimer disease centerJohns hopkins university school of medicineMinority aging research study

Free-range DNA in blood may signal dementia, frailty

Free range DNA fragments from a simple blood draw may be signs of higher risk of frailty and dementia, a new study shows.

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