Copy Link
Metabolic Limitations in Cancer
All cells in the body, including cancer cells, exist in different metabolic environments, and thus have different nutritional resources available to them, said
Mathew Vander Heiden. Cancer cells have especially high metabolic needs because by definition, they proliferate doubling the mass of proteins, nucleic acids, and lipids in order to go from one cell to two. Understanding how different types of cancer cells reorganize their metabolic pathways to accomplish this feat can bring insight into the role metabolism plays in cancer therapeutics.
Tissues solve their metabolic needs differently. Metabolism in brain cells, for example, differs from that in liver cells. These differences must be reflected in the gene expression patterns of the tissues’ metabolic networks. When a cell becomes cancerous, it takes its existing metabolic network, based on its environment, and reorganizes it to support its proliferation. That’s why cancers ex
According to Flurry Analytics, the percentage of paid apps on the App Store fell from 20 percent in 2011 to 10 percent in 2013.
That’s a 10 percent drop in two years, and the trend is likely to continue. In general, Flurry said, people seemed to want free content even if it meant putting up. Read More.