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BASIC RESEARCH Made to Be Invaded Mini gut models give scientists a front row seat to some of the most puzzling pathogen behaviors. by Monique Brouillette The foodborne bacteria Salmonella enterica begins its reproductive journey by hitching a ride on a tainted meal. After being swallowed it coasts to the hollow tube of the digestive tract, where it will grow and divide. But the bacterium must first propel itself through a 50-micron thick layer of viscous mucus in the walls of the intestines, using a whip-like flagellum as a kind of corkscrew. Once near the lining of the gut, it deploys a syringe-like protein to inject itself into a cell, where it can at last make copies of itself.

United statesUppsala lanNoord hollandPetra geiserAdithya sridharMarcela pasettiUppsala universityAmsterdam university medical centerUniversity of maryland school medicineMaryland schoolஒன்றுபட்டது மாநிலங்களில்நூற்த் ஹாலண்ட்ஆம்ஸ்டர்டாம் பல்கலைக்கழகம் மருத்துவ மையம்பல்கலைக்கழகம் ஆஃப் மேரிலாந்து பள்ளி மருந்துமேரிலாந்து பள்ளி