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Evolocumab Reduces MACE in Patients With and Without Multivessel CAD: FOURIER

The benefit in those with less atherosclerosis emerged late, highlighting the long-term benefits of LDL lowering.

United statesBaylor college of medicineVijay nambiMarc sabatineLayla abushamatSanofi regeneronAmerican college of cardiology heart associationJournal of the american college cardiologyAmerican collegeAmerican heart associationBaylor college

The Biggest News of 2023: TCTMD s Top 10

Major regulatory news and RCTs topped the list, but COVID-19 and the opioid pandemic had an impact, as did a UK TAVI furor.

United statesMarc sabatineLodoco agepha pharmaJohn calhoonSuzie brownMorton kernAmerican heart associationDrug administrationNovo nordiskSociety of thoracic surgeonsAgepha pharmaGlenfield hospitalOutgoing presidentAddress spurs shockThoracic surgeons president john calhoonEvolut low risk

Think Clinical Trials Are Working OK? Ask a Cancer Patient | American Enterprise Institute

Think Clinical Trials Are Working OK? Ask a Cancer Patient | American Enterprise Institute
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United statesMemorial sloan kettering cancer centerNew yorkMatt herperJake seligerJudy sewardBill crowleyMarc sabatineBess stillmanEugene braunwaldEileen faucherDrug developmentTufts centerInstitutional review boardsWhy clinical trialsMayo clinic

Trial Halted for Bleeding Reduction With Abelacimab in AF

The phase 2 AZALEA-TIMI 71 trial in AF shows "an overwhelming reduction" in major and clinically relevant nonmajor bleeding with investigational Factor XI inhibitor abelacimab vs rivaroxaban.

United statesDan bloomfieldMarc sabatineNational blood clot allianceDrug administrationAnthos therapeuticsThenew england journalNorth americaLatin americaMiddle eastLeslie lakeAtrial fibrillationF atrial fibrillationAnticoagulation therapyErebrovascular accidentVa cerebrovascular accident

ESC/EACTS Task Force Recommends Downgrading PCI in Left Main CAD

For those with LM CAD and a low SYNTAX score, PCI should be no longer be a class I recommendation, the group says.

Noord hollandUnited statesMarc sabatineRobert byrneEmanuele barbatoDavid taggartEuropean association for cardioEuropean association of percutaneous cardiovascular interventionsEuropean society of cardiologyPhd mater private networkAmerican heart association scientific sessionsSapienza university of romePhd university of oxfordEuropean societyEuropean associationCardio thoracic surgery