email article
Compared with open esophagectomy, hybrid minimally invasive esophagectomy (HMIE) i.e., thoracotomy plus laparoscopic gastric mobilization was associated with improved long-term survival in esophageal cancer, according to a follow-up study of a randomized French trial.
The difference is likely due to decreased postoperative complications, speculated the researchers, led by Frederiek Nuytens, MD, of Hôpital Claude Huriez in Lille.
As shown in the team s report in
JAMA Surgery, the 5-year post-hoc analysis of 207 esophageal cancer patients in the open-label multicenter randomized controlled phase III MIRO trial found that, although overall survival (OS) and disease-free survival (DFS) were comparable for the HMIE and open esophagectomy groups, 5-year OS with HMIE was slightly better at 59% (95% CI 48-68) compared with open esophagectomy at 47% (95% CI 37-57), for an HR of 0.71 (95% CI 0.48-1.06).