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Immunotherapy for Renal-Cell Carcinoma Saves Lives

A 5-year randomised, placebo-controlled trial of pembrolizumab found a 38% reduction in death vs placebo.

United kingdomUnited statesDana farber cancer instituteTonik choueiriEuropean medicines agencyHarvard medical schoolNew england journalMerck sharpMalignant kidney neoplasm renal cell cancer rcc carcinoma of theRenal cell carcinomaAlignant neoplasiaAlignant neoplasmBiologic therapyKidney cancerAdrenal cancerUk site content united kingdom

Groups Ask WHO to Recognize Chronic Kidney Disease Threat

Three international nephrology organizations call for World Health Organization recognition of CKD as a major noncommunicable mortality driver.

United statesManna francisSustainable development goalWorld health organizationInternational society of nephrologyEuropean renal associationAmerican society of nephrologyUnited nationsInternational societyAmerican societyNature reviewsChronic renal failure kidney ckd diseaseRenal failureEnal insufficiencyIdney insufficiencyKidney failure

Immune-Related AEs Predict Outcomes in Advanced GU Cancers

Patients with advanced GU cancers who had immune-related AEs from immunotherapy had better overall survival a phenomenon also reported for other cancer types.

United statesVishal navaniYaowen zhangUniversity of calgarySichuan universityWest china hospitalClinical oncology genitourinary cancers symposiumMedscape medical newsMedscape medicalMalignant kidney neoplasm renal cell cancer rcc carcinoma of theRenal cell carcinomaAlignant neoplasiaAlignant neoplasmLung cancerUng carcinomaAncer of the lung

Breakthrough : Adjuvant Pembro Ups Survival in Renal Cancer

KEYNOTE-564 is the first trial to demonstrate an overall survival benefit with adjuvant immunotherapy in patients with clear cell renal cell carcinoma.

United statesDana farber cancer institutePedroc barataTonik choueiriKidney cancer program at dana farber instituteAmerican society of clinical oncology genitourinary symposiumHarvard medical schoolDrug administrationLank centerAmerican societyClinical oncology genitourinary symposiumGenitourinary oncologyKidney cancer programGenitourinary medical oncology research programUniversity hospitals seidman cancer centerLancet oncology

Time for Universal Genetic Testing in Genitourinary Cancers

A new study supported universal germline genetic testing for genitourinary cancers to enhance risk assessment and guide tailored interventions.

United statesMouneeb choudryNational comprehensive cancer networkDepartment of urologyMayo clinicMayo clinic arizonaClinical oncology genitourinary cancersMalignant kidney neoplasm renal cell cancer rcc carcinoma of theRenal cell carcinomaGenomics genomic medicineAlignant neoplasiaAlignant neoplasmKidney cancerAdrenal cancerProstate carcinomaAlignant prostate neoplasm

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