The compound fendiline hydrochloride could be used to stimulate a patient’s own white blood cells to fight the disease more effectively, instead of trying to use drugs that directly kill the fungus itself.
Cystic fibrosis may be Vertex Pharmaceuticals’ commercial bread and butter, but the drugmaker shouldn’t be pigeonholed as a rare disease company, executives said on a call with analysts Thursday. T
When OxyContin maker Purdue Pharma and its founding family inked a $4.3 billion opioid settlement back in September 2021, the judge overseeing the case
Researchers from Duke and the University of California at Irvine screened a library of more than 1,000 compounds and discovered that an old, experimental cancer drug called kenpaullone enhances the expression of the gene KCC2, which is essential for silencing pain signals. The drug was effective in treating mouse models of pain from nerve injury and bone cancer, they reported.
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