Scientists at the University of California San Francisco (UCSF) have designed a group of synthetic molecules that could prevent the rejection of allogeneic cell transplants. Their strategy consisted of activating the immune checkpoints of different populations of immune cells from the cell surface, but avoiding the cytotoxicity of natural killer (NK) cells and macrophages that would destroy the transplanted cells.
Researchers at the Crick have been able to show for the first time a mechanism that enables the human immune system to eliminate the bacteria that causes tuberculosis (TB), offering a new potential target for therapies against TB and other bacterial infections. Click to read more.
Scientists at the University of Southampton’s Centre for Cancer Immunology, the UK’s first centre dedicated to cancer immunology research, have been awarded £2. Click to read more.