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Potential HIV vaccine component leads to strong protection in primates

To block infection from HIV, a successful vaccine will require a combination of ingredients, including at least three antibody targets and a substance that boosts immune responses.

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Duke Human Vaccine Institute expands to new Research Triangle Park campus

Duke Human Vaccine Institute expands to new Research Triangle Park campus
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Duke University: Duke Opens New Research Campus in Research Triangle Park

Duke University: Duke Opens New Research Campus in Research Triangle Park
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Duke Opens New Research Campus in Research Triangle Park | Duke School of Medicine

Duke Opens New Research Campus in Research Triangle Park | Duke School of Medicine
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Newly identified antibody can be targeted by HIV vaccines

E-Mail DURHAM, N.C. - A newly identified group of antibodies that binds to a coating of sugars on the outer shell of HIV is effective in neutralizing the virus and points to a novel vaccine approach that could also potentially be used against SARS-CoV-2 and fungal pathogens, researchers at the Duke Human Vaccine Institute report. In a study appearing online May 20 in the journal Cell, the researchers describe an immune cell found in both monkeys and humans that produces a unique type of anti-glycan antibody. This newly described antibody has the ability to attach to the outer layer of HIV at a patch of glycans the chain-like structures of sugars that are on the surfaces of cells, including the outer shells of viruses.

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