An investigational dual PPAR agonist modifies Alzheimer s pathology and shows cognitive benefit in adults with mild-to-moderate disease and high plasma pTau-217 ratio, early data show.
Psychiatric disorders are more common among people with dementia than those without it, according to results of a population-based cohort study. Depression was the most common comorbidity.
The risk for a dementia diagnosis before age 90 years was significantly higher among people with a history of PPI use, especially those who were diagnosed at a younger age.