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Researcher identifies way to prevent breast cancer stem-like cells from evading therapy
New research at the University of Alberta has revealed a way to increase the sensitivity to immunotherapy of a rare type of cells within a tumour that are responsible for treatment resistance and breast cancer progression. The study, recently published in the journal Cancer Letters, could pave the way to better treatment outcomes for patients.
The researchers looked at how to use a type of cell called gamma delta T-cells more effectively in immunotherapy to target breast cancer stem-like cells. T-cell immunotherapy is a promising new field, with researchers around the world working to develop treatments that use a patient’s own immune system to fight diseases such as cancer. However, most immunotherapy of this type focuses on the more conventional alpha beta T-cells.