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Uptake of monoclonal antibodies and antiviral therapies for COVID-19 in Scotland

SARS-CoV-2 has kept evolving since it was first detected in 2019. Virus mutations have affected transmissibility, virulence, and the effectiveness of vaccines and COVID-19 therapeutics. In Scotland, treatments recently made available for use in patients with COVID-19 are sotrovimab, a neutralising monoclonal antibody that targets SARS-CoV-2 spike proteins, and SARS-CoV-2-specific antiviral drugs that inhibit viral replication. The latter includes nirmatrelvir–ritonavir (Paxlovid, Pfizer), which inhibits viral protease, and molnupiravir, which increases viral RNA mutagenesis.

Patient collaboration in COVID-19 research: translating ideas to reality

Involving patients in all stages of health data research is a noble aim; however, there are not too many examples of it being successfully put into practice particularly not in real-time pandemic surveillance. In November, 2020, the Early Pandemic Evaluation and Enhanced Surveillance of COVID-19 (EAVE II) team created a unique collaboration, inviting a Public Advisory Group (PAG) of 15 patient and public contributors to work alongside university and Public Health Scotland staff to provide vital perspectives of the public on all areas of their COVID-19 research.

Covid Scotland: Half of hospitalised patients develop complication

Covid Scotland: Half of hospitalised patients develop complication
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A Rapid Systematic Review of Public Responses to Health Messages Encouraging Vaccination against Infectious Diseases in a Pandemic or Epidemic

Tang) - plus see below for full authors names and affiliations Determining the success of previous health campaigns relating to pandemics and epidemics can inform future communication strategies for promoting vaccine uptake. Even if people s expressed willingness to get a vaccine SARS-CoV-2, as gauged in global surveys, translates perfectly into vaccine uptake, it is still likely that vaccine hesitancy will impact the vaccination effort against SARS-CoV-2. The aim of this review was to identify and synthesise evidence relating to effective messaging for encouraging vaccination in order to prevent virus transmission during pandemics or epidemics, including COVID-19. In light of evidence of the promise that involving key stakeholders in the design of public health messaging holds (e.g., by fostering co-creation of materials with the understanding of those we wish to engage in target behaviours), the review also examines patient and public involvement (PPI).

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