Patients with low-risk ductal carcinoma in situ (DCIS) who skipped adjuvant radiotherapy after breast-conserving surgery had comparable five-year outcomes to those with high-risk DCIS who received adjuvant radiotherapy, according to results from the E4112 clinical trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.
Skipping adjuvant radiotherapy may not impact risk of recurrence or progression in patients with low-risk DCIS. MRI and a DCIS gene profile were used to stratify patients for treatment
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